Goals

Why this exists

Three frustrations, met repeatedly on both sides of a hospital-to-lab career, are what this site is a response to. The first is the reason the other two matter.

The lab only sees what gets published. Research is designed around the literature — that is the only record a scientist can work from. But the earliest and clearest signal about how a disease or a drug really behaves usually appears somewhere else: in a clinic room, in what a patient says is actually happening to them, in a pattern a doctor keeps noticing across their own patients. Very little of it becomes a paper. Publishing is not a clinician's job, and there is rarely the time, the funding, or the obligation to do it. So the observation ends in the consultation, the bench never hears about it, and the next hypothesis gets built without the one piece of information that might have shaped it.

Where this is heading. The long-range aim is to narrow that gap: one place where a clinician, a patient, and a researcher can each put an observation on the record — including observations that are not scientifically established, and ones that point against the accepted view — so that at minimum they are visible to whoever might go and test them properly. Held together, those accounts are a source of hypotheses, not a source of conclusions. None of that exists on this site today. It needs careful moderation, real privacy handling, and an unmistakable line between an observation and a finding before it could be built without doing harm. It is stated here as a direction, not as something you can use.

Research tooling costs too much. Software that does arithmetic a textbook already specifies — dose scaling, dilutions, buffer maths, pharmacokinetic fitting — is routinely sold on per-seat licences that a student, a small lab, or an underfunded institute cannot justify. The formulas are public. The calculators should be too.

The knowledge is split in two. Reliable information sits in journals most people cannot open or read; what is freely readable is often written to attract attention rather than to be accurate. Between the paywall and the clickbait there is very little written carefully, for free, at the level the reader actually needs.

What it covers

One scope, drawn deliberately wide: anything that meaningfully influences human health, kept in a single place instead of scattered across separate specialist sites.

• Drug discovery — how a molecule becomes a medicine: targets, preclinical work, dose translation, formulation, why candidates fail.
• Clinical research — trial design and phases, endpoints, safety monitoring, and how to read a published result without over-reading it.
• Nutrition and food science — diet, hydration, micronutrients, and the evidence behind everyday health advice.

Who it is for

Four readers, two registers. Someone managing a condition and a scientist reading outside their specialism need the same facts delivered very differently, so most subjects are written twice rather than pitched at an unhappy middle.

• Health Seeker — for the general public and for patients: plain language, no jargon left unexplained, practical rather than theoretical.
• Health Professional — for clinicians and researchers: mechanisms, indications, toxicities, and open questions, with the primary literature named.

Browse both libraries →

What this site will not do

• Give medical advice. Nothing here diagnoses, prescribes, or replaces a consultation. It is information, and information is not care.
• Decide a dose. The calculators are reference arithmetic for research use. They are not a clinical or veterinary dosing authority, and they carry no regulatory clearance of any kind.
• Claim validation it does not have. Where a tool has been checked, the checks are published. Where it has not, it says so.
• Pass off shared observations as evidence. If the space described above is ever built, every account in it will be labelled for what it is: an unverified personal or clinical observation. It will not be presented as a finding, it will not be used to recommend or discourage any treatment, and it will never be a reason to change what a doctor has told you.
• Sell anything, or collect what it does not need. No products, no subscriptions, no ads. The calculators run entirely in the browser and upload nothing.
• Promise dates. This is built part-time around a doctorate. There is no schedule to publish, so none is offered — things appear when they are finished and checked, not before.